In a heavily guarded compound, a small group of children are being studied in a programme to discover the cure to a virus that has ravaged the globe. They are the last hope the human race has for survival. 10-year-old MELANIE (Nanua) attends school lessons daily. Like any young girl she has a favourite teacher and a favourite subject, however, she is escorted to class in full body restraints and when they come for her, it is with guns drawn. Melanie and her fellow pupils are second-generation hybrids - part Hungry , part human. But unlike first generation Hungries , Melanie excels in the classroom, is acutely attentive, imaginative, highly intelligent and loves her favourite teacher, MISS JUSTINEAU (Arterton). Melanie s talents draw the attention of DR. CALDWELL (Close) who is searching for the key to the evolution of the virus. When the base is overrun by Hungries, Melanie escapes with Miss Justineau, SERGEANT PARKS (Considine) and Dr. Caldwell who is intent on using Melanie to synthesize a vaccine. Bound for a fortress-like enclave where society clings to life, can they survive? Does Melanie hold the key to unlocking a cure for the plague on course to destroy the human race?